Season 2

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As House and his team are working on the diagnosis of a man with a giant, swollen tongue, the husband of a former patient walks into House’s office and shoots him. House continues to treat his patient from his ICU hospital bed with the shooter, who has been shot by hospital security and hand-cuffed to his bed, as his roommate. When the after-effects of the shooting begin to impact House, he starts to question his own ability to diagnose properly. As his patient’s body deteriorates, House struggles through his self-doubt and must trust his team to find a way to solve the case.

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A 16-year-old Hurricane Katrina victim suffering from hallucinations as a result of the tragedy is brought to House by his former bandmate who recently found out the girl is his daughter. Although House fears his friend is being scammed, he takes the case. As he works his way through the girl’s lies so he can diagnose and treat her, he’s forced to tell a few lies of his own.

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A young mother has a seizure while bathing her newborn son and nearly drowns him. House and the team have two cases at one time as they try to save the infant and determine the cause of the mother’s seizures.

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Foreman continues to experience the same progression of symptoms as the police officer. When he realizes he may be facing imminent death, he calls his father who comes to his son’s side. As it comes down to a race against time, House believes the solution to the illness is in the police officer’s apartment.

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When a police officer with a gunshot wound to the head and uncontrollable laughter is admitted, House and the team are baffled. When Foreman begins showing the same symptoms, they race to determine the cause of the illness before Foreman’s condition takes the same path.

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House treats a 15 year old faith healer, while Wilson feels left out when he finds out House isn’t planning on inviting him to his weekly poker game.

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House has to work fast when a woman comes in with a life-threatening case of insomnia. Meanwhile Cameron is angry at Foreman for stealing an article she worked on.

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When a six-year-old boy is brought in with the same symptoms as another patient who died years ago under House’s care, House believes the cases are identical and he can predict the course of the boy’s illness. Meanwhile, the clinic hosts a poker night to benefit the oncology department.

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Melinda, a troubled teenage girl who is immuno-compromised as a result of the medications she must take after a heart transplant, has a severe allergic reaction and goes into shock when her boyfriend visits her. Meanwhile, House and Wilson continue to work out the problems in their new living arrangement.

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House believes a woman is trying to kill her husband and tries to find the proof to confirm his suspicions. When Wilson moves in with House after separating from his wife, he learns Wilson is a great cook.